Magnesium could help rare cases of depression and elevate mood overall

As you will read below, magnesium is important to have in proper balance to your body. Having lower levels of magnesium could cause major issues. Many mental illnesses seem to be positively impacted by the introduction of magnesium supplements. This also includes people with major depression, bi polar disorder and manics. While these individuals could never fully leave their medication they were able to greatly reduce their usage due to magnesium.

Magnesium deficiency alone can cause depression, behavior and personality changes, apathy, irritability and anxiety (Wacker WE. 1968 & Freyre AV. 1970 & Rasmussen HH. 1989). This is a serious mineral that is vital for our well being as people. Magnesium is required by over 300 chemical reactions in humans. (Shils ME. 1999) Individuals with lower magnesium also lack a metabolite (5-hydroxyindoleacetic acid or 5-HIAA) of serotonin. This means lower serotonin levels. (Banki CM. 1985 & Banki CM. 1986) Which means you will have a poor mood.

Poor magnesium amounts impairs receptors vital for wellbeing and coping with stress properly. If you have a high stress environment you may need more magnesium as stress increases magnesium requirements (Seelig MS. 1994) (Siwek M. 2005) (RA Buist. 1985), all of this is relevant to psychiatric conditions that go beyond depression.

In her paper Vitamins, Minerals and Mood, Dr. Bonnie Kaplan states: “… low magnesium levels were reported in 15 adult inpatients with schizophrenia and 10 with depression in comparison with healthy controls but not in 6 patients who were manic (Kirov & Tsachev,1990). Some studies have examined the potential efficacy of magnesium as an adjunctive therapy for patients with bipolar disorder. Heiden et al. (1999) administered intravenous magnesium sulphate to 10 patients with severe treatment-resistant mania.

“Even though the patients were still being treated with lithium (n =10), haloperidol (n = 5), and/or clonazepam (n = 10) for the duration of the study, medication dosages could be decreased significantly with the addition of magnesium sulphate to the treatment regimens. Hence, this is apparently another example of medication augmentation with micronutrient supplementation, in addition to the folic acid study cited above (Coppen & Bailey, 2000). Of the 10 patients, 7 also showed “marked improvement” in the Clinical Global Impression Scale (Guy, 1976). In treating patients with mania, Giannini, Nakoneczie, Melemis, Ventresco, and Condon (2000) compared the effects of verapamil in combination with magnesium oxide to a verapamil–placebo combination.

“Nine female patients with severe rapid-cycling bipolar disorder were treated in an open trial with either a magnesium compound or lithium for up to 32 weeks (Chouinard, Beauclair, Geiser, &Etienne, 1990). The magnesium had clinical effects equivalent to those of lithium in more than half the patients; 7 of the 9 (77.8%)patients showed a significant positive response” (Kaplan, 2007).

Magnesium is a vital mineral. Defenciencies in Magnesium will result in depression, short term memory loss, loss of iq, cognitive functions lowered. The good thing is that magnesium is one of the few minerals that when taken has been successful in what is considered rapid recovery of major depression, as well for traumatic brain injury, suicide, anxiety, irritability, insomnia, postpartum depression, cocaine, alcohol and tobacco abuse. This mineral is vital for individuals who are depressed feeling. Consistently taking this mineral for short and long terms will benefit you.


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